Persistent sadness or low mood
Loss of interest or pleasure in activities
Changes in appetite or weight
Sleep problems, including insomnia or oversleeping
Fatigue or low energy
Feeling worthless, guilty, or hopeless
Trouble concentrating or making decisions
Slowed thinking, speech, or movements
Irritability or restlessness
Social withdrawal or isolation
Frequent crying or tearfulness
Unexplained physical aches or pains
Neglect of personal hygiene or responsibilities
Increased use of alcohol or drugs
Talking about death, dying, or suicide
Self-harm or risky behavior
Noticeable decline in work, school, or daily functioning